Predictors of esophageal varices and first variceal bleeding in liver cirrhosis patients

Table 5 Performance of non-invasive markers for prediction of esophageal variceal bleeding (n = 34)

Non-invasive markers	Cut-off value	Sensitivity	Specificity	AUC (95%CI)1	P value
FIB-4	5.02	53%	54%	0.51 (0.40-0.62)	0.881
Fibrosis index	3.12	53%	45%	0.52 (0.40-0.61)	0.901
King score	37.16	65%	44%	0.50 (0.40-0.60)	0.978
APRI	1.66	59%	54%	0.53 (0.43-0.64)	0.550
PL/SD	828	53%	39%	0.45 (0.34-0.56)	0.398
AST/ALT	1.71	59%	54%	0.53 (0.42-0.64)	0.628
MELD	15.5	56%	52%	0.55 (0.44-0.65)	0.436

¹AUC (area under the curve) obtained from the receiver operating characteristic. AST/ALT: Aspartate aminotransferase (AST) to alanine aminotransferase (ALT) ratio; APRI: AST to platelet ratio index; FIB-4: Fibrosis-4-index; MELD: Model for end-stage liver disease; PC/SD: Platelet count to spleen diameter.