miR-29a promotes hepatitis B virus replication and expression by targeting SMARCE1 in hepatoma carcinoma

Figure 5 SMARCE1 is a target of miR-29a (n = 3). A: Wild-type (WT) and mutant (MUT) 3’-UTR binding sites are shown. The mutated bases are labelled with a horizontal line; B: Relative luciferase activity was measured in HEK293 cells co-transfected WT or MUT SMARCE1 3’-UTR with miR-17 mimic or miR-control; C-E: The relative mRNA (C) and protein (D and E) levels of SMARCE1 were measured in HepG2.2.15 cells transfected with miR-29a mimics or anti-miR-29a. Data represent the mean ± SD. ^aP < 0.05 vs miR-control.