Anti-inflammatory and anti-apoptotic effects of rosuvastatin by regulation of oxidative stress in a dextran sulfate sodium-induced colitis model

doi:10.3748/wjg.v23.i25.4559

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 7, 2017; 23(25): 4559-4568
Published online Jul 7, 2017. doi: 10.3748/wjg.v23.i25.4559

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Figure 7 Rosuvastatin attenuated apoptosis in a dextran sodium sulphate-induced colitis model. Western blot showing protein levels of cleaved caspase-3, caspase-7, and PARP. Rosuvastatin attenuated the increase in cleaved caspase-3, caspase-7, and PARP in DSS-treated mice. PARP: Poly (ADP-ribose) polymerase; DSS: Dextran sodium sulphate; Ro: Rosuvastatin.

Citation: Shin SK, Cho JH, Kim EJ, Kim EK, Park DK, Kwon KA, Chung JW, Kim KO, Kim YJ. Anti-inflammatory and anti-apoptotic effects of rosuvastatin by regulation of oxidative stress in a dextran sulfate sodium-induced colitis model. World J Gastroenterol 2017; 23(25): 4559-4568
URL: https://www.wjgnet.com/1007-9327/full/v23/i25/4559.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i25.4559