Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis

Table 3 Statistical expression of relative abundances disruption in the study groups at species level

Species	PSC	PSC-IBD	UC
Rothia mucilaginosa	↑↑↑	↑↑	NS
Lactobacillus salivarius	NS	↑↑↑	NS
Streptococcus infantis	↑↑	↑↑	NS
Streptococcus alactolyticus	↑↑	↑↑	NS
Streptococcus equi	↑↑	↑↑	NS
Veillonella dispar	↑↑	↑↑	NS
Veillonella parvula	↑	↑↑	NS
Prevotella copri	↓	↓↓↓	NS
Adlercreutzia equolifaciens	↓↓↓	NS	NS
Faecalibacterium prausnitzi	↓	↓↓↓	↓↓
Coprococcus catus	↓	↓↓	↓
Ruminococcus gnavus	↓↓	↓↓	↓↓↓
Akkermansia muciniphila	NS	NS	↓↓↓
Butyricicoccus pullicaecorum	NS	NS	↓↓↓
Clostridium colinum	NS	NS	↓↓↓

Only taxa with P < 0.01 in at least one group are presented. ↑↑↑, ↓↓↓: Increased, decreased with P < 0.001; ↑↑, ↓↓: P < 0.01; ↑, ↓: P < 0.05; NS: Non-significant; PSC: Primary sclerosing cholangitis; IBD: Inflammatory bowel disease; UC: Ulcerative colitis.