Hepatitis C virus NS5A region mutation in chronic hepatitis C genotype 1 patients who are non-responders to two or more treatments and its relationship with response to a new treatment

Table 3 Type of response according to the type of treatment received n (%)

	Total, n = 129	NVR, n = 81	SVR, n = 48	OR (95%CI)	P value
IFN	16 (12)	14 (88)	2 (12)	0.05 (0.01-0.3)	0.001
IFN + RBV	40 (31)	27 (68)	13 (32)	0.2 (0.06-0.5)	0.001
pegIFN + RBV	43 (34)	32 (74)	11 (26)	0.12 (0.04-0.4)	0.00
DAAs	30 (23)	8 (27)	22 (73)	1

This analysis excluded the first 72 treatments, which presented statistical bias, because one of the inclusion criteria was that these should be non-responders. DAAs: Direct-acting antivirals; IFN: Interferon; NVR: No virological response; RBV: Ribavirin; SVR: Sustained virological response.