Copyright
©The Author(s) 2017.
World J Gastroenterol. Jul 7, 2017; 23(25): 4480-4490
Published online Jul 7, 2017. doi: 10.3748/wjg.v23.i25.4480
Published online Jul 7, 2017. doi: 10.3748/wjg.v23.i25.4480
Table 3 Mutations identified in the different nuclear receptor coregulator genes in human colorectal cancer n (%)
Coregulator | 216 United States patients (COAD-US) | 187 Chinese patients (COCA-CN) | ||
Patients affected | Mutations | Patients affected | Mutations | |
NCOA1 | 6 (2.78) | 7 | 9 (4.81) | 14 |
NCOA2 | 10 (4.63) | 10 | 26 (13.90)1 | 32 |
NCOA3 | 21 (9.72)1 | 17 | 9 (4.81) | 10 |
NCOA6 | 19 (8.80)1 | 21 | 8 (4.28) | 10 |
PPARGC1A | 10 (4.63) | 12 | 5 (2.67) | 6 |
EP300 | 13 (6.02)1 | 15 | 14 (7.49)1 | 21 |
CREBBP | 18 (8.33)1 | 20 | 7 (3.74) | 11 |
MED1 | 3 (1.39) | 4 | 6 (3.21) | 6 |
NCOR1 | 21 (9.72)1 | 25 | 23 (12.30)1 | 48 |
NCOR2 | 41 (18.98)1 | 43 | 30 (16.04)1 | 40 |
NRIP1 | 5 (2.31) | 5 | 6 (3.21) | 10 |
MTA1 | 11 (5.09)1 | 11 | 12 (6.42)1 | 13 |
- Citation: Triki M, Lapierre M, Cavailles V, Mokdad-Gargouri R. Expression and role of nuclear receptor coregulators in colorectal cancer. World J Gastroenterol 2017; 23(25): 4480-4490
- URL: https://www.wjgnet.com/1007-9327/full/v23/i25/4480.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i25.4480