Naringenin prevents experimental liver fibrosis by blocking TGFβ-Smad3 and JNK-Smad3 pathways

doi:10.3748/wjg.v23.i24.4354

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Jun 28, 2017; 23(24): 4354-4368
Published online Jun 28, 2017. doi: 10.3748/wjg.v23.i24.4354

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Figure 7 Naringenin effect on macroscopic and microscopic hepatic architecture in CCl₄-treated rats. Macroscopic aspect of livers in control rats (A), carbon tetrachloride (CCl₄)-treated rats (B), CCl₄ plus naringenin rats (CCl₄ + NAR) (C), and NAR alone rats (D). Hematoxylin and Eosin stain in livers of control rats (E), CCl₄-treated rats (F), CCl₄ + NAR rats (G), and rats administered with NAR alone (H). Masson’s trichromic staining in livers of control rats (I), CCl₄-treated rats (J), CCl₄ + NAR (K), and NAR alone rats (L). Bar scale = 50 μm. Magnification × 100.

Citation: Hernández-Aquino E, Zarco N, Casas-Grajales S, Ramos-Tovar E, Flores-Beltrán RE, Arauz J, Shibayama M, Favari L, Tsutsumi V, Segovia J, Muriel P. Naringenin prevents experimental liver fibrosis by blocking TGFβ-Smad3 and JNK-Smad3 pathways. World J Gastroenterol 2017; 23(24): 4354-4368
URL: https://www.wjgnet.com/1007-9327/full/v23/i24/4354.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i24.4354