Maytenus erythroxylon Reissek (Celastraceae) ethanol extract presents antidiarrheal activity via antimotility and antisecretory mechanisms

Table 3 Effect of the oral administration of EtOH extract obtained from the leaves of Maytenus erythroxylon on the organ index of male and female mice for 14 d

Sex	Organ index1	Vehicle	EtOHE-Me
		(NaCl 0.9%)	(2000 mg/kg)
Female	Liver	52.66 ± 6.68	53.59 ± 41.61NS
	Heart	4.27 ± 0.74	3.86 ± 0.56NS
	Kidneys	11.40 ± 0.81	10.81 ± 2.31NS
	Spleen	5.53 ± 0.83	5.16 ± 1.03NS
Male	Liver	51.59 ± 2.57	52.33 ± 4.16NS
	Heart	4.71 ± 0.75	4.24 ± 0.45NS
	Kidneys	12.18 ± 1.31	13.16 ± 0.97NS
	Spleen	5.53 ± 0.94	4.78 ± 0.37NS

¹Data are presented in mg/g and expressed as mean ± SD.

^NSNo significant differences (P > 0.05) between treated (EtOHE-Me) vs non-treated (NaCl 0.9%) mice. EtOHE-Me: Ethanol extract of Maytenus erythroxylon.