Intestinal anti-inflammatory activity of Ground Cherry (Physalis angulata L.) standardized CO2 phytopharmaceutical preparation

Table 4 Effects of the PACO₂ standardized extract (25, 50 or 100 mg/kg) on cytokine levels in acute phase response of intestinal inflammation induced by trinitrobenzenesulphonic acid

Group	IFN-γ	TNF-α	IL1-β	IL-6	IL-10
Non-colitic	78.2 ± 7.9c	121.2 ± 7.0a	1395.0 ± 136.9a	421.1 ± 45.3a	467.1 ± 31.1a
TNBS control	125 ± 20.4	240.3 ± 34.3	2205.0 ± 147.4	893.8 ± 105.5	675.5 ± 38.6
PACO2, 25 mg/kg	92.1 ± 8.6	246.6 ± 34.3	1867.0 ± 221.4	891.9 ± 87.09	674.5 ± 40.4
PACO2, 50 mg/kg	67 ± 11.7c	167.9 ± 23.6	2106.0 ± 128.9	563.4 ± 55.5c	626.9 ± 66.5
PACO2, 100 mg/kg	76.4 ± 12.7c	205.5 ± 34.5	2323.0 ± 154.1	649.5 ± 86.9	537.4 ± 41.1

Data are expressed as mean ± SE of the mean.

^cP ≤ 0.05 and

^aP ≤ 0.01.