Intestinal anti-inflammatory activity of Ground Cherry (Physalis angulata L.) standardized CO2 phytopharmaceutical preparation

Table 2 Macroscopic effects of the PACO2 standardized extract (25, 50 or 100 mg/kg) in acute phase response of intestinal inflammation induced by trinitrobenzenesulphonic acid

Group	Damage score, 0-101	Extension of lesion, cm2	Colonic weight, mg/cm2	Diarrhea3	Adherence3
Non-colitic	0a	0a	82.7 ± 2.10a	0%a	0%a
TNBS-control	7 (2-8)	2.55 ± 0.28	136.0 ± 5.87	87.50%	81.25%
PACO2 - 25 mg/kg	7 (5-8)	2.44 ± 0.18	135.0 ± 6.86	100.00%	71.42%
PACO2 - 50 mg/kg	7 (2-9)	2.11 ± 0.34	124.0 ± 7.72	85.71%	71.42%
PACO2 - 100 mg/kg	7 (4-9)	2.93 ± 0.20	162.0 ± 5.04	100.00%	57.14%

¹Score data are expressed as the median (range);

²Extension of lesion and colonic weight data are expressed as the mean ± SE of the mean;

³Diarrhea and adherence were analyzed by Fisher's exact test.

^aP ≤ 0.01.