Indole phytoalexin derivatives induce mitochondrial-mediated apoptosis in human colorectal carcinoma cells

Table 3 IC₅₀ (μmol/L) of tested compounds in different cell lines after 72 h incubation

Compound	Cancer Cell Lines
	CaCo-2	HCT116	3T3
K-452	> 100	> 100	> 100
K-453	67.39 ± 0.78	32.22 ± 1.14	60.55 ± 3.35
K-455	> 100	> 100	> 100
K-459	> 100	> 100	> 100
K-462	> 100	> 100	> 100
K-463	74.18 ± 0.001	33.04 ± 2.67	61.13 ± 2.25
K-465	35.66 ± 6.49	33.74 ± 2.78	34.94 ± 2.01
K-466	> 100	> 100	> 100
K-467	> 100	> 100	> 100
K-471	> 100	> 100	> 100

Data are presented as the mean ± SD of three independent experimental determinations performed in triplicate.