Inhibition of N-methyl-N-nitrosourea-induced gastric tumorigenesis by Liuwei Dihuang Pill in db/db mice

Figure 5 Effects of Liuwei Dihuang Pill on insulin and insulin-like growth factor signaling pathways. A: A representative blot is presented. IGF-1R, AKT and their phosphorylated status were determined by western blotting. β-actin served as a loading control; B: Intensity of protein bands was determined with Image-J 1.46r software. The expression ratios of target proteins relative to β-actin were calculated. Data represent the mean ± SE. ^aP < 0.05, ^bP < 0.01 vs control. IGF-1R: Insulin-like growth factor-1 receptor.