Inhibition of N-methyl-N-nitrosourea-induced gastric tumorigenesis by Liuwei Dihuang Pill in db/db mice

Figure 4 Effects of Liuwei Dihuang Pill on gene expression in gastric tissues. mRNA expression of IGF-1, IGF-1R, IGF-2, IGF-2R and insulin receptor was determined in stomach tissues by qRT-PCR. mRNA expression was normalized to that of GAPDH. Data represent the mean ± SE. ^aP < 0.05, ^bP < 0.01 vs control. IGF-1/2: Insulin-like growth factor-1 or 2; IGF-1/2R: Insulin-like growth factor-1 or 2 receptor; LDP: Liuwei Dihuang Pill; qRT-PCR: Quantitative reverse transcription-polymerase chain reaction.