Inhibition of N-methyl-N-nitrosourea-induced gastric tumorigenesis by Liuwei Dihuang Pill in db/db mice

Figure 1 Hematoxylin and eosin staining of stomach tissue. A: Gastric dysplasia in non-diabetic control group (db/m); B: Gastric dysplasia in diabetic control group (db/db); C: Gastric cancer in diabetic control group (db/db); D: Gastric dysplasia in metformin-treated group (db/db); E: Gastric dysplasia in LDP-treated group (db/db). The black arrows indicate cell dysplasia with irregular and hyperchromatic cell nuclei. The red arrows show invasive gastric cancer cells in the submucosa. Bar represents 50 μm. LDP: Liuwei Dihuang Pill; MNU: N-methyl-N-nitrosourea.