Association of keratin 8/18 variants with non-alcoholic fatty liver disease and insulin resistance in Chinese patients: A case-control study

Table 3 Clinical features of non-alcoholic fatty liver disease patients harboring significant keratin variants

	Keratin variant carriers		P value
	No (n = 190)	Yes (n = 10)
Sex (male, %)	155 (81.58)	9 (90.00)	0.436
Age (yr)	40.75 ± 9.87	42.60 ± 10.63	0.603
Diastolic pressure (mmHg)	82.67 ± 10.47	85.80 ± 9.38	0.330
Systolic pressure (mmHg)	130.79 ± 14.82	134.20 ± 17.07	0.550
BMI (kg/m2)	26.26 ± 2.91	26.10 ± 3.09	0.877
ALT (U/L)	35.93 ± 18.35	38.40 ± 25.30	0.767
AST (U/L)	34.03 ± 13.08	30.40 ± 9.31	0.265
TC (mmol/L)	5.67 ± 1.02	6.10 ± 1.69	0.453
TG (mmol/L)	2.85 ± 2.14	3.00 ± 2.35	0.850
HDL (mmol/L)	1.09 ± 0.24	1.10 ± 0.18	0.828
LDL (mmol/L)	3.31 ± 0.94	3.65 ± 1.12	0.374
FBG (mmol/L)	5.38 ± 1.43	5.91 ± 1.44	0.281
FINS (mmol/L)	11.17 ± 4.52	12.73 ± 6.00	0.439
HOMA-IR	2.64 ± 1.14	3.25 ± 1.50	0.237
UA (μmol/L)	414.06 ± 96.89	381.50 ± 89.88	0.292

Data are presented as mean ± SD. BMI: Body mass index; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; TC: Total cholesterol; TG: Triglyceride HDL: High-density lipoprotein; LDL: Low-density lipoprotein; FBG: Fasting blood glucose; FINS: Fasting insulin; UA: Uric acid.