Relationship between serum adenosine deaminase levels and liver histology in autoimmune hepatitis

Table 3 General features and laboratory findings of autoimmune hepatitis patients according to inflammatory activity

	Interface hepatitis			P value
	Mild (n = 9)	Moderate (n = 18)	Severe (n = 25)
Age in years	39.3 ± 14.5	41.1 ± 11.0	39.7 ± 13.9	0.927
Sex, F/M	6-3	12-6	6-19	0.759
ALT as × ULN	3.9 (IQR = 1.6)	7.3 (IQR = 11.3)	10.9 (IQR = 12)	0.0321
Serum IgG in gr/dL	1810 (IQR = 745)	1955 (IQR = 570)	2390 (IQR = 1205)	0.0291
ADA in U/L	15.2 ± 3.5	23.1 ± 10.0	30.9 ± 7.0	< 0.0011
ADA > 20 U/L, n (%)	0	9 (50)	24 (96)	< 0.0011

¹Indicated statistically significant difference. ADA: Adenosine deaminase; AIH: Autoimmune hepatitis; ALT: Alanine aminotransferase; IQR: Interquartile range; ULN: Upper limit of normal.