Validation of a serum microRNA panel as biomarkers for early diagnosis of hepatocellular carcinoma post-hepatitis C infection in Egyptian patients

Table 5 Significant relations among enrolled circulating miRNAs in hepatocellular carcinoma patients

	miR-138b	miR-494	miR-145	miR-375	miR-214-5p	miR-1269	miR-125b
miR-138b		r = 0.471	r = 0.521	NS	r = 0.649	r = 0.862	r = 0.685
		P = 0.008	P = 0.006		P < 0.0002	P < 0.0001	P < 0.0001
miR-494	r = 0.471		r = 0.538	NS	NS	r = 0.418	NS
	P = 0.008		P = 0.003			P = 0.021
miR-145	r = 0.521	r = 0.538		r = 0.460	r = 0.449	r = 0.453	NS
	P = 0.006	P = 0.003		P = 0.038	P < 0.009	P = 0.019
miR-375	NS	NS	r = 0.460		r = 0.884	NS	NS
			P = 0.038		P < 0.0001
miR-214-5p	r = 0.649	NS	r = 0.449	r = 0.884		r = 0.621	r = 0.518
	P < 0.0002		P < 0.009	P < 0.0001		P = 0.0005	P = 0.005
miR-1269	r = 0.862	r = 0.418	r = 0.453	NS	r = 0.621		r = 0.602
	P < 0.0001	P = 0.021	P = 0.019		P = 0.0005		P = 0.001
miR-125b	r = 0.685	NS	NS	NS	r = 0.518	r = 0.602
	P < 0.0001				P = 0.005	P = 0.001

r is the Spearman rho coefficient. NS: Non-significant.