Cyclooxygenase 2 in liver dysfunction and carcinogenesis: Facts and perspectives

doi:10.3748/wjg.v23.i20.3572

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May 28, 2017 (publication date) through Jul 27, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 28, 2017; 23(20): 3572-3580
Published online May 28, 2017. doi: 10.3748/wjg.v23.i20.3572

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Figure 1 Main regulation and effects of cyclooxygenase-2 in liver. COX-2 and PGE₂ exert protection against many liver injuries and promote proliferation of hepatocytes and inhibition of apoptosis and necrosis of hepatic cells. The contribution to inflammation remains controversial depending on the moment of COX-2 expression.

Citation: Martín-Sanz P, Casado M, Boscá L. Cyclooxygenase 2 in liver dysfunction and carcinogenesis: Facts and perspectives. World J Gastroenterol 2017; 23(20): 3572-3580
URL: https://www.wjgnet.com/1007-9327/full/v23/i20/3572.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i20.3572