Tracing overlapping biological signals in mid-infrared using colonic tissues as a model system

Figure 4 Analysis of different parameters to indicate the changes in composition within a crypt. A: Distribution of different metabolites in the various zones: Glucose/phosphate [I (1030 cm^-1)/I (1080 cm^-1)], Carbohydrates/amide II [I (1045 cm^-1)/I (1545 cm^-1)], RNA/DNA [I (1121 cm^-1)/I (1020 cm^-1)], and Phosphate/amide II [I (1080 cm^-1)/I (1545 cm^-1)]. Each line represents a crypt and the dark line represents the average. A few crypts are shown along with the averages to indicate the pattern; B: Correlation between different parameters (Solid square-phosphate/amide II and solid circle-carbohydrate/amide II) and the RNA/DNA ratio along the crypt. The lines are only an indicator of the trends. The values within the box indicate the correlation coefficients of the different parameters with the RNA/DNA ratio.