Mitochondrial carnitine palmitoyl transferase-II inactivity aggravates lipid accumulation in rat hepatocarcinogenesis

Figure 4 Immunohistochemical analysis of carnitine palmitoyl transferase II expression. The CPT-II contents of rat hepatic tissues in the different rat groups were analyzed by immunohistochemistry. A: Liver sections of control rats with normal diet; B: Liver sections of the fatty liver rats with high-fat diet without 2-fluorenyl acetamide (2-FAA); C: Liver sections of the degeneration rats with high-fat diet containing 2-FAA, at early stage; D: Liver sections of precancerous rats with high-fat diet containing 2-FAA, at interim stage; E: Liver sections of cancerous rats with high-fat diet containing 2-FAA, at later stage; F: The relative quantitative analysis of CPT-II in the liver tissue; A-E: The original magnification was × 200; A1-E1: The original magnification was × 400. ^aP < 0.05. CPT-II: Carnitine palmitoyl transferase-II.