Mitochondrial carnitine palmitoyl transferase-II inactivity aggravates lipid accumulation in rat hepatocarcinogenesis

Figure 3 Dynamic alteration of carnitine palmitoyl transferase-II expression in rat livers. The CPT-II contents of rat hepatic tissues in the different rat groups were analyzed during hepatocyte malignant transformation. A: Liver sections of control rats with normal diet; B: Liver sections of the fatty liver rats with high-fat diet without 2-fluorenylacetamide (2-FAA); C: Liver sections of the degeneration rats with high-fat diet containing 2-FAA, at early stage; D: Liver sections of precancerous rats with high-fat diet containing 2-FAA, at interim stage; E: Liver sections of cancerous rats with high-fat diet containing 2-FAA, at later stage. ^aP < 0.05. CPT-II: Carnitine palmitoyl transferase-II.