Recombinant adeno-associated virus carrying thymosin β4 suppresses experimental colitis in mice

Figure 8 Adeno-associated virus carrying thymosin β₄ attenuated the acceleration of colonic mucosal cell proliferation following dextran sulfate sodium and 2,4,6-trinitrobenzene sulfonic acid treatments. Colonic cell proliferation was determined by PCNA immunostaining in dextran sulfate sodium (DSS) (A) and 2,4,6-trinitrobenzene sulfonic acid (TNBS) models (C). PCNA label indexes (PCNA LIs) of the DSS model (B) and TNBS model (D) were calculated. Error bars indicate the SD. Scale bars = 50 μm. AAV: Adeno-associated virus; Tβ₄: Thymosin β₄.