Association between polymorphisms of the APOBEC3G gene and chronic hepatitis B viral infection and hepatitis B virus-related hepatocellular carcinoma

Table 2 Baseline characteristics of study subjects, n (%)

Group	Healthy controls,	Chronic HBV infection patients				P value3
	n = 299	Non-HCC		HBV-related HCC
		n = 370	P value1	n = 287	P value2
Male	247 (82.6)	295 (79.7)	0.345	246 (85.7)	0.304	0.921
Age, M (P25, P75)	50 (45, 55)	49 (42, 55)	0.078	50 (46, 56)	0.589	0.408
Smoking			0.392		0.003	0.292
Ever	113 (37.8)	128 (34.6)		144 (50.2)
Never	186 (62.2)	242 (65.4)		143 (49.8)
Drinking			0.036		0.804	0.241
Ever	122 (40.8)	122 (33.0)		120 (41.8)
Never	177 (59.2)	248 (67.0)		167 (58.2)

P values represent the non-HCC¹, HCC², and chronic HBV³ patients compared to the healthy controls. HBV: Hepatitis B virus; HCC: Hepatocellular carcinoma.