Diabetes recurrence after metabolic surgeries correlates with re-impaired insulin sensitivity rather than beta-cell function

Figure 4 Serum insulin after oral glucose administration. Serum insulin levels after oral glucose gavage (1 g/kg) at baseline (A), 4 (B) and 12 (C) wk postoperatively. No significant differences were observed in SG and DJB groups at 4 or 12 wk postoperatively. Insulin levels in response to oral glucose gavage increased in HFD and LFD rats at 12 wk postoperatively. ^aP < 0.05 vs Sham group at 12 wk postoperatively. SG: Sleeve gastrectomy; SG-LFD: SG rats with common low-fat diet; SG-HFD: SG with high-fat diet; DJB: Duodenal-jejunal bypass; DJB-LFD: DJB rats with LFD; DJB-HFD: DJB rats with HFD.