Effects of heme oxygenase-1-modified bone marrow mesenchymal stem cells on microcirculation and energy metabolism following liver transplantation

Figure 8 Inducible nitric-oxide synthase expression in the liver after liver transplantation. A: Immunohistochemistry (IHC) of inducible nitric-oxide synthase (iNOS); B: IHC integrated optical density (IOD) of iNOS; C: iNOS protein levels. iNOS protein levels: postoperative day (POD) 1: HO-1/BMMSCs group vs NS group: 0.21 ± 0.02 vs 0.35 ± 0.07 (P < 0.05). POD5: HO-1/BMMSCs vs NS group: 0.48 ± 0.03 vs 0.30 ± 0.05 (P < 0.01); HO-1/BMMSCs group vs BMMSCs group: 0.48 ± 0.03 vs 0.34 ± 0.02 (P < 0.01). POD7: HO-1/BMMSCs group vs BMMSCs group vs NS group: 0.38 ± 0.01 vs 0.52 ± 0.04 vs 0.83 ± 0.03 (P < 0.01). POD14: HO-1/BMMSCs group vs BMMSCs group vs NS group: 0.45 ± 0.06 vs 0.73 ± 0.08 vs 0.86 ± 0.03 (P < 0.05). ^aP < 0.05 vs NS group, ^cP < 0.05 vs HO-1/BMMSCs group.