Relationship between use of selective serotonin reuptake inhibitors and irritable bowel syndrome: A population-based cohort study

Table 5 Hazard ratio of irritable bowel syndrome among selective serotonin reuptake inhibitor and antidepressant users

	n	aHR1	(95%CI)	P value
Overall
Non-SSRIs	77327	1.00	(reference)
Non-SSRIs + other antidepressants	1285	1.33	(0.75-2.36)	0.338
SSRIs + other antidepressants	2872	1.30	(0.84-2.01)	0.235
SSRIs only	16781	1.82	(1.50-2.21)	< 0.001

¹aHR, adjusted by age, sex, urbanization, family income, area of residence, occupation, anti-psychotics and the comorbidities listed in Table 1. SSRIs: Selective serotonin reuptake inhibitors.