Benefit of neoadjuvant concurrent chemoradiotherapy for locally advanced perihilar cholangiocarcinoma

doi:10.3748/wjg.v23.i18.3301

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 14, 2017; 23(18): 3301-3308
Published online May 14, 2017. doi: 10.3748/wjg.v23.i18.3301

Table 3 Efficacy of neoadjuvant chemoradiotherapy n (%)

	Neoadjuvant chemoradiotherapy (n = 12)	Non-neoadjuvant chemoradiotherapy (n = 45)	P value¹
Alteration of TNM stage before and after surgery			0.01
Upstaging	0 (0)	11 (24.4)
No change	1 (8.3)	11 (24.4)
Downstaging	11 (91.7)	23 (51.1)
R0 resection	10 (83.3)	30 (66.7)	0.32
Surgical pathology
Microvascular invasion	6 (50.0)	29 (64.4)	0.51
Perineural invasion	7 (58.3)	44 (97.8)	< 0.01
Lymph node metastasis	3 (25.0)	25 (55.6)	0.06
Perioperative complications	2 (16.7)	11 (24.4)	0.71

¹P values were determined using a Mann-Whitney test for continuous variables and a χ² test (Fisher’s exact test, Pearson and Mantel-Haenszel χ² test) for categorical variables.

Citation: Jung JH, Lee HJ, Lee HS, Jo JH, Cho IR, Chung MJ, Park JY, Park SW, Song SY, Bang S. Benefit of neoadjuvant concurrent chemoradiotherapy for locally advanced perihilar cholangiocarcinoma. World J Gastroenterol 2017; 23(18): 3301-3308
URL: https://www.wjgnet.com/1007-9327/full/v23/i18/3301.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i18.3301