Octogenarian liver grafts: Is their use for transplant currently justified?

Table 1 Donor characteristics n (%)

Characteristics	Donors ≤ 65 yr	Donors ≥ 80 yr	P value
	Group A (n = 102)	Group B (n = 51)
Donor age (yr)	46.9 ± 15.0	83.5 ± 2.8	< 0.001
Sex (male/female)	62/40	13/38	< 0.001
Body mass index	26.9 ± 4.5	27.2 ± 5.4	0.670
> 30	26 (25.7)	15 (29.4)	0.800
Cause of donor death			0.006
Cerebrovascular	64 (62.7)	39 (76.5)
Head trauma	24 (23.5)	12 (23.5)
Anoxia	11 (10.8)	0
Other causes	3 (3.0)	0
ICU stay (h)	67.6 ± 79.6	49.9 ± 47.6	0.007
Vasopressor use	78 (76.5)	33 (64.7)	0.120
Cardiac arrest	26 (25.5)	1 (2.0)	< 0.001
Total bilirubin (mg/dL)	0.77 ± 0.74	1.05 ± 1.25	0.049
GOT (IU/L)	63 ± 76	30 ± 19	< 0.001
GPT (IU/L)	55 ± 69	22 ± 18	< 0.001
GGT (IU/L)	54 ± 61	38 ± 44	0.058
Prothrombin rate (%)	80 ± 20	77 ± 23	0.460
Sodium (meq/L)	147 ± 10	143 ± 5	0.001
Type of steatosis
Microsteatosis	26 (25.5)	11 (21.5)	0.590
Macrosteatosis	53 (52.0)	19 (37.3)	0.086
Grade of macrosteatosis
Mild (< 30%)	45 (44.1)	19 (37.3)	0.290
Moderate (30%-60%)	6 (5.9)	0 (0)	0.077
Severe (> 60%)	2 (2.0)	0 (0)
Preservation injury			0.140
Mild	39 (30.4)	14 (27.5)
Moderate	30 (26.5)	13 (25.5)
Severe	6 (5.9)	3 (5.8)
CIT (min)	406 ± 181	476 ± 132	0.091
WIT (min)	65 ± 15	59 ± 12	0.170

LT: Liver transplantation; ICU: Intensive care unit; GOT: Glutamic oxaloacetic transaminase; GPT: Glutamic pyruvic transaminase; GGT: γ-glutamyl transpeptidase.