Low-grade slightly elevated and polypoid colorectal adenomas display differential β-catenin-TCF/LEF activity, c-Myc, and cyclin D1 expression

Table 1 Demographic and clinical characteristics of study participants

Characteristics	Elevated cohort, n = 24 (%)	Polypoid cohort, n = 23 (%)	P value
Age, mean ± SD	54.1 ± 9.4	53.9 ± 9.4	> 0.05
Sex (male/female)	13/11	11/12	> 0.05
BMI, mean ± SD	23.8 (3.2)	23.9 (3.3)	> 0.05
Smoker (yes/no)	9/15 (38/62)	9/14 (39/61)	> 0.05
Excess alcohol (yes/no)	3/24 (13)	3/23 (13)	> 0.05
Lesion site (prox/dist/rect)	16/5/3 (67/21/12)	6/9/8 (26/39/35)	< 0.05
Diameter (mm), mean (range)	8 (2-50)	9 (3-32)	> 0.05
Paris classification	0-IIa, 24 (100)	0-I, 23 (100)	< 0.05
Histology, T/TV/V/S	14/8/2/0 (58/33/8/0)	11/9/3/0 (48/39/13/0)	> 0.05
Pathological grade	Low-grade, 24 (100)	Low-grade, 23 (100)	> 0.05

Prox: Proximal colon (including the cecum, ascending colon, and transverse colon); Dist: Distal colon (including the sigmoid colon, descending colon, and splenic flexure); Rect: Rectal; T: Tubular; TV: Tubulovillous; V: Villous; S: Serrated; BMI: Body mass index.