Effects of Hwangryunhaedok-tang on gastrointestinal motility function in mice

Figure 3 Effects of the four components of extract of Hwangryunhaedok-tang on gastric emptying. A: 5-HT4 receptor agonist (mosapride, 5 mg/kg) or a dopamine receptor antagonist (domperidone, 5 mg/kg) was administered in distilled water. After a 24 h fast, animals (n = 6/each group) were orally dosed with four components of HHTE, that is, A: Gardeniae Fructus (GF); B: Scutellariae Radix (SR); C: Coptidis Rhizoma (CR); or D: Phellodendri Cortex (PC), at the indicated dosages. GE percentages were calculated as described in Materials and Methods. Bars represent mean ± SE. ^bP < 0.01, ^eP < 0.001. Significantly different from normal controls. Mosa.: Mosapride; Dom.: Domperidone.