Non-ALT biomarkers for markedly abnormal liver histology among Chinese persistently normal alanine aminotransferase-chronic hepatitis B patients

Table 1 Baseline demographic and clinical characteristics of all subjects with normal alanine aminotransferase level

	All (n = 155)	HBeAg-positive (n = 86)	HBeAg-negative (n = 69)
Age (yr)	39.7 ± 9.9	42.9 ± 8.9	37.2 ± 9.9
Male, n (%)	84 (54.2)	52 (60.9)	34 (48.8)
HBV DNA (logIU/mL)	5.8 ± 2.1	4.3 ± 1.4	6.9 ± 1.9
WBC (109/mL)	5.9 ± 3.1	5.9 ± 4.4	5.8 ± 1.5
PLT (109/mL)	190.08 ± 62.9	182.29 ± 57.7	196.3 ± 66.5
ALT (U/L)	26.0 ± 8.7	25.0 ± 9.2	26.8 ± 8.1
AST (U/L)	24.6 ± 6.6	24.1 ± 6.1	25.1 ± 7.0
ALP (U/L)	68.1 ± 20.1	67.1 ± 17.2	68.9 ± 22.2
GGT (U/L)	21.8 ± 14.6	21.1 ± 11.9	22.3 ± 16.5
TB (g/L)	13.6 ± 6.7	13.6 ± 7.5	13.6 ± 6.1
PT (s)	11.4 ± 1.1	11.4 ± 1.0	11.4 ± 1.4
TT (s)	19.1 ± 1.7	18.8 ± 1.8	19.3 ± 1.5
A/G ratio	1.7 ± 0.4	1.8 ± 0.4	1.7 ± 0.4
Cr (μmol/L)	70.2 ± 14.6	70.0 ± 15.2	70.4 ± 14.2
TBA (μmol/L)	8.7 ± 14.1	6.3 ± 6.0	10.7 ± 17.9
GLB (g/L)	27.2 ± 4.3	26.9 ± 4.1	27.5 ± 4.4
ALB (g/L)	45.6 ± 4.0	46.7 ± 4.0	44.5 ± 3.9

A/G ratio: Albumin to globulin (A/G) ratio; ALB: Albumin; ALP: Alkaline phosphatase; ALT: Alanine aminotransferase; AST: Aspartate transaminase; Cr: Creatinine; GGT: Gamma-glutamyl transpeptidase; GLB: Globulin; PT: Prothrombin time; TB: Total bilirubin; TBA: Total bile acid; TT: Thrombin time.