Comparative study of ROR2 and WNT5a expression in squamous/adenosquamous carcinoma and adenocarcinoma of the gallbladder

Table 2 Relationship of ROR2 and WNT5a expression with the clinicopathologic characteristics of gallbladder squamous/adenosquamous carcinoma n (%)

Pathologic characteristic	Number of cases	ROR2			WNT5a
		Positive cases	χ2	P value	Positive cases	χ2	P value
Pathological type
Squamous carcinoma	26	16 (61.5)	0.612	0.434	17 (65.4)	0.141	0.708
Adenosquamous carcinoma	20	10 (50.0)			12 (60.0)
Differentiation
High	16	5 (31.3)	9.123	0.010	8 (50.0)	1.827	0.401
Moderate	24	15 (62.5)			17 (70.8)
Poor	6	6 (100.0)			4 (66.7)
Maximal diameter of the mass in cm
≤ 3	20	7 (35.0)	6.669	0.010	9 (45.0)	4.945	0.026
≥ 3	26	19 (73.1)			20 (76.9)
Gallstones
No	18	11 (61.1)	0.253	0.615	12 (66.7)	0.167	0.683
Yes	28	15 (53.6)			17 (60.7)
TNM stage
I + II	12	4 (33.3)			4 (33.3)
III	20	10 (50.0)	7.824	0.023	14 (70.0)	6.411	0.041
IV	14	12 (85.7)			11 (78.6)
Lymph node metastasis
No	17	5 (29.4)	8.065	0.005	7 (41.2)	6.720	0.010
Yes	29	21 (72.4)			22 (75.9)
Invasion of the surrounding tissue
No	16	5 (31.3)	6.376	0.011	7 (43.8)	3.920	0.048
Yes	30	21 (70.0)			22 (73.3)
Surgical procedure
Radical	14	4 (28.6)	7.374	0.022	5 (35.7)	77.677	0.019
Palliative	18	11 (61.1)			12 (66.7)
Unresected	14	11 (78.6)			12 (85.7)