Comparative study of ROR2 and WNT5a expression in squamous/adenosquamous carcinoma and adenocarcinoma of the gallbladder

Table 1 Comparison of the clinicopathologic characteristics of gallbladder squamous/adenosquamous carcinomas and adenocarcinomas with the expression of ROR2 and WNT5a n (%)

Clinicopathologic characteristic	SC/ASC,n = 46	AC,n = 80	χ2	P value
Sex
Male	19 (41.3)	26 (32.5)	0.986	0.352
Female	27 (58.7)	54 (67.5)
Age, yr
≤ 45	3 (6.5)	16 (20.0)	4.143	0.042
> 45	43 (93.5)	64 (80.0)
Degree of differentiation
High	16 (34.8)	27 (33.8)	8.515	0.014
Moderate	24 (52.2)	25 (31.3)
Poor	6 (13.0)	28 (35.0)
Maximal diameter of the mass, cm
≤ 3	20 (43.5)	50 (62.5)	4.280	0.039
> 3	26 (56.5)	30 (37.5)
Gallstones
No	18 (39.1)	42 (52.5)	2.093	0.148
Yes	28 (60.9)	38 (47.5)
TNM stage
I + II	12 (26.1)	21 (26.3)	0.287	0.866
III	20 (33.5)	38 (47.5)
IV	14 (30.4)	21 (26.3)
Lymph node metastasis
No	17 (37.0)	30 (37.5)	0.004	0.952
Yes	29 (63.0)	50 (62.5)
Invasion of the surrounding tissue
No	16 (34.8)	31 (38.8)	0.197	0.658
Yes	30 (62.5)	49 (61.3)
Surgical procedure
Radical	14 (30.4)	26 (32.5)	0.215	0.898
Palliative	18 (39.1)	28 (35.0)
Unresected	14 (30.4)	26 (32.5)
Average survival time	10.07 (4-25)	10.34 (3-27)	0.014	0.906
ROR2
-	20 (43.5)	29 (36.2)	0.642	0.386
+	26 (56.5)	51 (63.8)
WNT5a
-	17 (37.0)	31 (38.7)	0.040	0.858
+	29 (63.0)	49 (61.3)

AC: Adenocarcinoma; SC/ASC: Squamous/adenosquamous carcinoma.