Clinical characteristics of peptic ulcer perforation in Korea

Table 5 Multivariate analysis for the risk factors of non-steroidal anti-inflammatory drugs-associated perforated peptic ulcer compared with ​non-Helicobacter pylori, non-non-steroidal anti-inflammatory drug associated perforated peptic ulcer

Variables	Unadjusted OR (95%CI)	P value	Adjusted OR (95%CI)	P value
Sex (men)	0.16 (0.05-0.55)	0.003
Age	1.12 (1.06-1.17)	< 0.001	1.09 (1.04-1.16)	0.001
BMI (kg/m2)	0.89 (0.74-1.07)	0.210
Alcohol consumption	0.23 (0.07-0.79)	0.020
Current smoking	0.32 (0.11-0.98)	0.050
Previous ulcer history	1.24 (0.35-4.32)	0.740
Comorbidity	9.63 (2.78-33.39)	< 0.001	4.11 (1.03-16.48)	0.050

All variables with P ≤ 0.2 by univariate analysis were analyzed by multivariate analysis. BMI: Body mass index.