Clinical utility of the platelet-lymphocyte ratio as a predictor of postoperative complications after radical gastrectomy for clinical T2-4 gastric cancer

Table 3 Predictive factors for grade 2 or higher complications according to the Clavien-Dindo system: Univariate and multivariable analyses

Variables	Univariate			Multivariable
	Odds ratio	95%CI	P value	Odds ratio	95%CI	P value
Age (≥ 65 yr)	1.26	0.73-2.23	0.410
Gender (male)	4.22	1.88-11.3	< 0.001	4.17	1.78-11.5	< 0.001
Preoperative symptoms	0.95	0.55-1.64	0.864
Diabetes mellitus	1.14	0.49-2.45	0.755
Cardiac comorbidities	1.81	1.02-3.18	0.041	1.55	0.83-2.87	0.166
Pulmonary comorbidities	1.26	0.40-3.40	0.669
Body mass index (≥ 22)	1.62	0.94-2.81	0.084
Preoperative PLR (< 0.71)	2.94	1.66-5.35	< 0.001	3.32	1.82-6.25	< 0.001
Tumor location (lower third)	0.62	0.34-1.11	0.107
Macroscopic tumor size (> 50 mm)	1.19	0.69-2.05	0.534
UICC cT (cT4)	1.30	0.67-2.69	0.457
UICC cN (cN1-3)	1.75	1.01-3.08	0.045	1.69	0.93-3.08	0.083
Operative procedure (total gastrectomy)	2.42	1.39-4.23	0.002	2.43	1.35-4.43	< 0.001

Analyses were performed using binomial logistic analysis. PLR: Platelet-lymphocyte ratio; UICC: Union for International Cancer Control.