Noninvasive molecular analysis of Helicobacter pylori: Is it time for tailored first-line therapy?

Table 1 Antibiotic susceptibility (clarithromycin): studies on Helicobacter pylori stool DNA by real time polymerase chain reaction

Ref.	Reference standard	Sensitivity	Specificity	Clarithromycin resistance
Scaletsky et al[32]	PCR on gastric biopsy	83.3%	100.0%	26.7%
1Vécsei et al[38]	Culture	89.2%	100.0%	45.1%
Noguchi et al[33]	Culture	NA	NA	20.4%
Rimbara et al[34]	Culture	96.6%	91.3%	13.3%
1Booka et al[35]	Culture	NA	NA	31.0%
Schabereiter-Gurtner et al[36]	Culture	98.0%	98.0%	24.4%
Fontana et al[37]	Culture	100.0%	100.0%	1.6%

¹Pediatric population. NA: Not assessed.