Proposed criteria to differentiate heterogeneous eosinophilic gastrointestinal disorders of the esophagus, including eosinophilic esophageal myositis

Figure 3 Subepithelial eosinophilic esophagitis (case 6). A: Endoscopy showing the compressed lumen. Characteristic findings for eosinophilic esophagitis such as longitudinal furrows, white plaques, or fixed rings are not seen. High-resolution manometry (HRM) results, showing highly disrupted distal contractile integral (42.5 mmHg/[s•cm], lower insert). The patient was diagnosed with failed peristalsis based on the Chicago classification criteria; B: Mucosal histology by conventional biopsy at 100 × magnification. The white triangle indicates upward papillae elongation. In the upper-right inset, there is an absence of eosinophil infiltration in the epithelium (400 × magnification). Subepithelial eosinophilia (35 eosinophils per high-power field) is shown in the left lower inset (400 × magnification).