Proposed criteria to differentiate heterogeneous eosinophilic gastrointestinal disorders of the esophagus, including eosinophilic esophageal myositis

Figure 2 Eosinophilic esophagitis (case 3). A: Endoscopy shows longitudinal furrows (yellow triangles) and white plaques (red arrow) in the medial esophagus, and the presence of fixed rings in the lower esophagus [upper insert (white triangle)]. High-resolution manometry (HRM) results showing highly disrupted distal contractile integral (DCI; 54.8 mmHg/[s•cm], lower insert). The patient was diagnosed with failed peristalsis based on the Chicago classification criteria; B: Histology at 100 × magnification, showing significant eosinophil inflammation was observed (50 eosinophils per high-power field) in the esophageal epithelium with dilated intercellular spaces (lower insert).