Transition after pediatric liver transplantation - Perceptions of adults, adolescents and parents

doi:10.3748/wjg.v23.i13.2365

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Apr 7, 2017 (publication date) through Nov 5, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastroenterol. Apr 7, 2017; 23(13): 2365-2375
Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2365

Table 3 Characteristics of patients and responders vs non-responders n (%)

	Adults (post-transfer), [n = 138 (F/M = 57/81), median age: 24.6 yr]			Adolescents (pre-transfer), [n = 57 (F/M = 24/33), median age: 14.7 yr]
	Responder	Non-responder	P value	Responder	Non-responder	P value
n	54 (39)	84 (61)		38 (67)	19 (33)
Female	15 (26)	42 (74)	0.01²	17 (71)	7 (29)	0.78²
Male	39 (48)	42 (52)	0.01²	21 (64)	12 (36)	0.78²
Survey-age (yr), mean ± SD	25.6 ± 5.70	24.1 ± 5.22	0.12¹	14.7 ± 2.14	14.8 ± 2.04	0.88¹
OLT-age (yr), mean ± SD	8.3 ± 5.60	8.6 ± 5.22	0.80¹	7.5 ± 5.25	6.0 ± 3.90	0.30¹
OLT-survey (yr), mean ± SD	16.8 ± 6.88	14.9 ± 6.82	0.11¹	7.2 ± 4.88	8.9 ± 3.44	0.21¹
BPAR, mean ± SD	1.02 ± 0.83	1.04 ± 1.20	0.48¹	0.84 ± 0.82	0.42 ± 0.61	0.06¹
BPAR outpatient, mean ± SD	0.51 ± 0.68	0.64 ± 1.11	0.75¹	0.55 ± 0.72	0.37 ± 0.60	0.34¹
#OLT, mean ± SD	1.37 ± 0.57	1.29 ± 0.51	0.27¹	1.16 ± 0.50	1.21 ± 0.54	0.81¹
Re-OLT outpatient, mean ± SD	ND	ND	ND	0.11 ± 0.31	0.16 ± 0.50	0.95¹
LDLT	0	0	ND	6 (16)	1 (5)	0.41²
ALV	7 (13)	10 (7)	> 0.9²	5 (13)	2 (11)	> 0.9²
“In-Center-Transfer”	30 (61)	32 (44)	0.04²	ND	ND	ND
Chronic rejection	6 (5)	10 (8)	0.82²	0	0	ND

¹Mann-Whitney U test, 2-sided;

²Exacter-Fisher’s exact test, 2-sided. Survey-age: Age at day of responding the survey; OLT-age: Age at orthotopic liver transplantation; OLT-survey: Years between liver transplantation and survey; BPAR: Biopsy proven acute rejection, median amount per patient; BPAR outpatient: BPAR after first discharge after OLT; #OLT: Average number of liver transplantations per patient; Re-OLT outpatient: Amount of Re-OLT after first discharge from hospital-stay for first OLT; LDLT: Total number of living donor liver transplantations and the percentage within the responder or non-responder group; ALV: Number of acute live failures and the percentage within the responder or non-responder group; In-Center-Transfer: Patients transferred from the pediatric to adult clinic within Hannover Medical School in each group and percentage within the corresponding group; ND: Not determined.

Citation: Junge N, Migal K, Goldschmidt I, Baumann U. Transition after pediatric liver transplantation - Perceptions of adults, adolescents and parents. World J Gastroenterol 2017; 23(13): 2365-2375
URL: https://www.wjgnet.com/1007-9327/full/v23/i13/2365.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i13.2365