Review
Copyright ©The Author(s) 2017.
World J Gastroenterol. Mar 28, 2017; 23(12): 2124-2140
Published online Mar 28, 2017. doi: 10.3748/wjg.v23.i12.2124
Figure 2
Figure 2 Interactive biological networks are affected by environmental factors. Environmental exposures, including dietary constituents and a dysbiotic microbiota, affect the host’s genome and epigenome in a redundant and overlapping fashion, determining aberrant immunity and defective intestinal homeostasis, which lead to the development of inflammatory bowel disease.