Systematic review: The placebo effect of psychological interventions in the treatment of irritable bowel syndrome

Table 3 Placebo treatment and placebo response rate

Ref.	Placebo treatment	Primary outcome measure	Duration of treatment1	Follow-up	Placebo response	Treatment response
Craske et al[23] 2011	Psycho-educational support	BSS index	10 wk	3 mo	59% (13/22)	62% (29/47)1
						54% (22/41)2
Drossman et al[24] 2003	Psycho-educational support	Composite score3	12 wk		37.3% (19/51)	70% (77/110)
Gaylord et al[25] 2011	Support group	IBS-SSS	8 wk	3 mo	45.2% (17.6/39)	68.8% (27.4/36)
					53.1% (20.7/39)	75% (27/36)
Moser et al[26] 2013	Supportive talks	IBS-IS	12 wk	12 mo	40.9%( 18/44)	60.8%(28/46)
					25% (11/44)	54.3% (25/46)
Payne et al[27] 1995	Psycho-educational support	CPSR	8 wk	3 mo	25% (3/12)	75% (9/12)
					18% (2/12)	83% (10/12)
Shinozaki[28] 2010	Psycho-educational support	AR	8 wk		30% (3/10)	81.8% (9/11)

¹Cognitive behavioral treatment;

²Stress management;

³Composite score: Mc-Gill Pain Questionnaire; IBS-QOL; satisfaction with treatment; global well-being. IBS: Irritable bowel syndrome; BSS: Bowel syndrome severity index; IBS-SSS: IBS-Symptom Severity Score; IBS-IS: IBS-Impact Scale; AR: Adequate relief; CPSR: Composite primary symptom reduction.