Chemotherapy response evaluation in a mouse model of gastric cancer using intravoxel incoherent motion diffusion-weighted MRI and histopathology

Figure 5 IVIMDW images and signal intensity decay with increasing b-values. A: IVIMDW images acquired at increasing b-values in a representative mouse from the treated group and one from the control group; B: Within the tumor ROI, the averaged signal intensity decay as a function of the b-value is plotted (day 7) by both the bi-exponential and mono-exponential model, respectively. For the treated mouse, D* = 1.27 × 10^-3 mm²/s, fp = 57.3% and ADC = 0.69 × 10^-3 mm²/s. For the control mouse, D* = 2.15 × 10^-3 mm²/s, fp = 17.2% and ADC = 0.55 × 10^-3 mm²/s.