Quality of life after total vs distal gastrectomy with Roux-en-Y reconstruction: Use of the Postgastrectomy Syndrome Assessment Scale-45

Table 3 Multi-variate analysis of main outcome measures

		Main outcome measures	Multiple regression analysis
Domains	Subdomains		Type of gastrectomy [TGRY]		Postoperative period (mo)		Age (yr)		Gender [male]		Approach [laparoscopic]		Celiac branch of vagal nerve [preserved]
			β	P value	β	P value	β	P value	β	P value	β	P value	β	P value	R2	P value
Symptoms	Subscales (GSRS and PGSAS items)	Esophageal reflux SS2	0.298	< 0.0001		≥ 0.1		≥ 0.1	(-0.079)	0.0179	(-0.060)	0.0828		≥ 0.1	0.096	< 0.0001
		Abdominal pain SS2	(-0.089)	0.0096	(-0.060)	0.0932		≥ 0.1	-0.181	< 0.0001		≥ 0.1		≥ 0.1	0.045	< 0.0001
		Meal-related distress SS2	0.295	< 0.0001		≥ 0.1	(-0.064)	0.0531	-0.114	0.0006		≥ 0.1		≥ 0.1	0.101	< 0.0001
		Indigestion SS2	0.166	< 0.0001	-0.114	0.0012		≥ 0.1	(-0.083)	0.0138	(-0.071)	0.0436	(-0.063)	0.0639	0.057	< 0.0001
		Diarrhea SS2	0.107	0.0020	(-0.063)	0.0774		≥ 0.1	(-0.092)	0.0074		≥ 0.1		≥ 0.1	0.024	0.0026
		Constipation SS2
		Dumping SS2	0.189	< 0.0001		≥ 0.1	-0.123	0.0006	-0.129	0.0003		≥ 0.1		≥ 0.1	0.071	< 0.0001
	Total	Total symptom score2	0.216	< 0.0001		≥ 0.1		> 0.1	(-0.092)	0.0115		≥ 0.1		> 0.1	0.059	< 0.0001
Living status	Body weight	Change in body weight	0.315	< 0.0001		≥ 0.1	(-0.068)	0.0449	(-0.088)	0.0086		≥ 0.1		≥ 0.1	0.114	< 0.0001
	Meals (amount)	Ingested amount of food per meal1	0.202	< 0.0001		≥ 0.1	(-0.060)	0.0838		> 0.1		≥ 0.1		≥ 0.1	0.048	< 0.0001
		Necessity for additional meals	0.273	< 0.0001		≥ 0.1	-0.083	0.0142	(-0.093)	0.0057		≥ 0.1		≥ 0.1	0.090	< 0.0001
	Meals (quality)	Quality of ingestion SS1,2
	Social activity	Ability for working	0.127	0.0003	(-0.079)	0.0289	0.163	< 0.0001	(-0.073)	0.0371		≥ 0.1		≥ 0.1	0.052	< 0.0001
QOL	Dissatisfaction	Dissatisfaction with symptoms	0.158	< 0.0001	(-0.083)	0.0199		≥ 0.1	-0.105	0.0022		≥ 0.1		≥ 0.1	0.041	< 0.0001
		Dissatisfaction at the meal	0.291	< 0.0001	(-0.081)	0.0193		≥ 0.1	(-0.072)	0.0313		≥ 0.1		≥ 0.1	0.093	< 0.0001
		Dissatisfaction at working	0.220	< 0.0001		≥ 0.1		≥ 0.1		> 0.1		≥ 0.1		≥ 0.1	0.051	< 0.0001
		Dissatisfaction for daily life SS2	0.268	< 0.0001	(-0.086)	0.0145		≥ 0.1	(-0.087)	0.0097		≥ 0.1		≥ 0.1	0.083	< 0.0001
	SF-8	Physical component summary1,2	0.109	0.0016		≥ 0.1	-0.124	0.0004	(-0.079)	0.0210		≥ 0.1		≥ 0.1	0.034	< 0.0001
		Mental component summary1,2		≥ 0.1		≥ 0.1		≥ 0.1		≥ 0.1		≥ 0.1		≥ 0.1
									The interpretation of effect size				r, β		R2
									(none-very small)				(0.100) >		(0.020) >
									Small				0.100 ≤		0.020 ≤
									Medium				0.300 ≤		0.130 ≤
									Large				0.500 ≤		0.260 ≤

Outcome measures with¹: higher score indicating better condition. Outcome measures without¹: higher score indicating worse condition. The main outcomes with² are integrated subscales. If β is positive, the score of the outcome measure of the patients belonging to the category in [brackets] is higher in cases when the factor is a nominal scale, and he score of outcome measure of the patients with larger values is higher in cases when the factor is a numeral scale.