Quality of life after total vs distal gastrectomy with Roux-en-Y reconstruction: Use of the Postgastrectomy Syndrome Assessment Scale-45

Table 1 Uni-variate analysis of main outcome measures following total gastrectomy and distal gastrecrtomy procedures

Domains	Subdomains	Main outcome measures	TGRY		DGRY		Uni-variate analysis
			mean	SD	mean	SD	P value	Cohen's d
Symptoms	PGSAS subscales (GSRS and PGSAS items)	Esophageal reflux subscale (items 10, 11, 13, 24)2	2.0	1.0	1.5	0.7	< 0.0001	0.58
		Abdominal pain subscale (items 9, 12, 28)2	1.8	0.8	1.7	0.8	0.0571	(0.13)
		Meal-related distress subscale (items 25-27)2	2.6	1.1	2.1	0.9	< 0.0001	0.56
		Indigestion subscale (items 14-17)2	2.3	0.9	2.0	0.8	< 0.0001	0.29
		Diarrhea subscale (items 19, 20, 22)2	2.3	1.2	2.1	1.1	0.0066	(0.19)
		Constipation subscale (items 18, 21, 23)2	2.1	0.9	2.1	1.0	≥ 0.1
		Dumping subscale (items 30, 31, 33)2	2.3	1.1	2.0	1.0	< 0.0001	0.31
	Total	Total symptom score (above seven subscales)2	2.2	0.7	1.9	0.7	< 0.0001	0.38
Living status	Body weight	Change in body weight	-13.8%	7.9%	-8.9%	6.6%	< 0.0001	0.66
	Meals(amount)	Ingested amount of food per meal	6.4	1.9	7.2	2.0	< 0.0001	0.42
		Necessity for additional meals	2.4	0.8	1.9	0.8	< 0.0001	0.57
	Meals (quality)	Quality of ingestion subscale1 (items 38-40)2	3.8	0.9	3.8	0.9	≥ 0.1
	Social activity	Ability for working	2.0	0.9	1.8	0.9	0.0006	0.24
QOL	Dissatisfaction	Dissatisfaction with symptoms	2.1	1.0	1.8	0.9	< 0.0001	0.28
		Dissatisfaction at the meal	2.8	1.1	2.2	1.1	< 0.0001	0.57
		Dissatisfaction at working	2.1	1.1	1.7	1.0	< 0.0001	0.41
		Dissatisfaction for daily life subscale (items 43-45)2	2.3	0.9	1.9	0.9	< 0.0001	0.51
	SF-8	Physical component summary (PCS)1 (items 1-8)2	49.6	5.6	50.8	5.6	0.0029	0.21
		Mental component summary (MCS)1 (items 1-8)2	49.2	6.0	49.8	5.7	0.0974	(0.11)
					The interpretation of effect size			Cohen's d
					(none-very small)			(0.20 >)
					Small			0.20 ≤
					Medium			0.50 ≤
					Large			0.80 ≤

Outcome measures with¹: higher score indicating better condition. Outcome measures without¹: higher score indicating worse condition. The main outcomes with² are integrated subscales. Each subscale is calculated as the mean of composed items or subscales, except PCS or MCS of SF-8.