Predictive factors for compliance with transanal irrigation for the treatment of defecation disorders

Table 2 Comparison of background variables, baseline demographics, severity scores, anorectal physiological testing, defecography, and colonic transit times of adopters and of non-adopters who discontinued transanal irrigation during the first year n (%)

Variables	Adopters	Non-adopters	P value
	n = 46	n = 44
Age (yr)	55.9 ± 13.9	51 ± 17.8	0.29
Gender
Female	36 (78)	38 (86)	0.46
Male	10 (22)	6 (14)
BMI	25.4 ± 4.3	23.6 ± 4.9	0.05
Main symptom
Constipation	22 (48)	28 (64)	0.19
FI	24 (52)	16 (36)
Type of constipation	n = 42	n = 39
Slow transit	8 (19)	6 (15.4)	0.48
Obstructed defecation	17 (40.5)	21 (53.8)
Mixed	17 (40.5)	12 (30.8)
Type of FI	n = 28	n = 24	0.82
Urge	7 (25)	5 (21)
Passive	19 (68)	18 (75)
Mixed	2 (7)	1 (4)
Main causes of constipation/FI
Neurological disease	19 (41.3)	14 (31.8)	0.47
Slow transit constipation	6 (13)	8 (18.2)	0.70
Obstructed defaecation syndrome	8 (17.4)	11 (25)	0.53
FI	13 (28.3)	11 (25)	0.91
Prior surgical procedures	11 (24)	17 (39)	0.13
	n = 42	n = 40
Severe defecation disorders according to severity scores	32 (76)	31 (77)	0.99
Anorectal manometry:	n = 38	n = 33
Resting pressure (cmH2O)	66.6 ± 30.7	57.2 ± 27.3	0.20
Squeeze pressure (cmH2O)	57.8 ± 56.5	59.6 ± 67.7	0.81
Threshold volume (mL)	21.9 ± 15.7	15.7 ± 6.9	0.16
Maximum tolerated volume (mL)	225.1 ± 98.6	234.5 ± 145.6	0.83
Rectal compliance (mL/cmH2O)	4.1 ± 2.4	4.2 ± 4	0.51
Colonic transit time	n = 31	n = 33
Right colon (h)	28.1 ± 19.7	29.9 ± 18.4	0.54
Left colon (h)	35.5 ± 23.6	38 ± 25.4	0.60
Recto-sigmoid colon (h)	23.6 ± 21.8	29 ± 26.6	0.53
Total (h)	90.2 ± 35.4	88.4 ± 44.3	0.97
Defecography
Rectal prolapse	n = 29	n = 22
or recto-anal procidentia	9 (31)	6 (27)	0.22

Values are expressed as mean ± SD. BMI: Body mass index; FI: Fecal incontinence.