Hyperplasia vs hypertrophy in tissue regeneration after extensive liver resection

Figure 4 Size distribution of hepatocyte nuclei, the only evident change being detected after 24 h. A: Showing nuclear size distribution over time following PH. The most prominent change is observed at 24 h post-PH (green line), with the appearance of a larger nuclear class size (arrow), which is only marginally present at later time points; B: Reporting percent of binucleated hepatocytes detected on 2D sections in control rat liver and at 10 d post-PH. A relative decrease is observed after PH; C (control rat liver) and D (10 d post-PH) show immunofluorescent staining for Phalloidin with nuclei were counterstained with DAPI. Binucleated hepatocytes are easily discerned. Data are mean ± SE of 5 animals per group. ^bP < 0.01, vs control group. PH: Partial surgical hepatectomy.