Serum HER2 as a predictive biomarker for tissue HER2 status and prognosis in patients with gastric cancer

doi:10.3748/wjg.v23.i10.1836

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 23, Issue 10

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (7986)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-3) series, Tables (1-3) series.

Item

Count

PDF

487

WORD

288

HTML

4553

Figures (1-3)

258

Tables (1-3)

257

Sum=5843

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

795

Download

1348

Sum=2143

Mar 14, 2017 (publication date) through Jan 24, 2025

Times Cited of This Article

Times Cited (14)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastroenterol. Mar 14, 2017; 23(10): 1836-1842
Published online Mar 14, 2017. doi: 10.3748/wjg.v23.i10.1836

Table 2 Diagnostic performance of serum HER2 extracellular domain for tissue HER2 status at different cut-off values

Cut-off values (ng/mL)	True positive	False positive	True negative	False negative	Sensitivity (95%CI)	Specificity (95%CI)
15.00¹	23	35	165	16	0.59 (0.42-0.74)	0.83 (0.77-0.88)
24.75²	21	15	185	18	0.54 (0.37-0.70)	0.93 (0.88-0.96)

¹Value recommended by FDA for breast cancer;

²Value determined by Youden’s index in ROC plot.

Citation: Shi HZ, Wang YN, Huang XH, Zhang KC, Xi HQ, Cui JX, Liu GX, Liang WT, Wei B, Chen L. Serum HER2 as a predictive biomarker for tissue HER2 status and prognosis in patients with gastric cancer. World J Gastroenterol 2017; 23(10): 1836-1842
URL: https://www.wjgnet.com/1007-9327/full/v23/i10/1836.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i10.1836