miRNA-133a-UCP2 pathway regulates inflammatory bowel disease progress by influencing inflammation, oxidative stress and energy metabolism

Figure 2 Significantly increased UCP2 and decreased miR-133a levels in the dextran sulfate sodium group. A: Immunohistochemical staining (upper panel) and Western blot (lower panel) showed increased UCP2 expression in the cytoplasm of colons from mice in the dextran sulfate sodium (DSS) group; B: qRT-PCR showed significantly increased UCP2 mRNA in the DSS group; C: qRT-PCR showed significantly decreased miR-133a mRNA in the DSS group. ^bP < 0.01.