Expression of trefoil factors and TWIST1 in colorectal cancer and their correlation with metastatic potential and prognosis

Figure 1 TFF1, TFF3 and TWIST1 expression trends in colorectal cancer (A), adjacent normal tissue (B), metastatic lymph node (C), and liver metastasis (D). Compared with normal mucosal tissue, colorectal cancer tissues expressed significantly higher TFF1 and TWIST1 and lower TFF3. Compared to primary colorectal cancer tissue, there were no statistical differences in TFF3 and TWIST1 expression in metastatic lymph node or liver metastatic tissue. But disparity in TFF1 expression between metastatic lymph node and primary colorectal cancer had statistical significance.