Copyright
©The Author(s) 2017.
World J Gastroenterol. Jan 7, 2017; 23(1): 25-41
Published online Jan 7, 2017. doi: 10.3748/wjg.v23.i1.25
Published online Jan 7, 2017. doi: 10.3748/wjg.v23.i1.25
Table 3 Results of contrast-enhanced harmonics-endoscopic ultrasound assessment for solid pancreatic masses in various studies
Ref. | Type of study | Contrast agent | No. of patients | MI | Hypoenhancement as a sign of adenocarcinoma | EUS diagnostic rate | EUS-FNA diagnostic rate |
Napoleon et al[18] 2010 | Endoscopy | Sonovue | 35 | 0.4 | Sn = 89% | Sn = 79% | |
PC-18 | Sp = 88% | Sp = 100% | |||||
NET-9 | PPV = 89% | PPV = 100% | |||||
CP-7 | NPV = 88% | NPV = 54% | |||||
Acc = 88.5% | Acc = 83% | ||||||
Fusaroli et al[12] 2010 | Prospective | Sonovue | 90 | 0.36 radial | Sn = 96% | Sn = 86% | |
PC-51, NET-13, CP-13 | 0.28 linear | Sp = 64% | Sp = 18% | ||||
Ac = 82% | Ac = 57% | ||||||
Ang et al[19] 2011 | Definity | 29 (PC-16, CP-4, Other-9) | 0.3 | Better detection of vascular invasion and tumor margins | - | ||
Matsubara et al[20] 2011 | Retrospective | Sonazoid | 91 | 0.2 | Sn = 87.5% | - | - |
Sp = 77.8% | |||||||
Hocke et al[13] 2012 | Prospective | Sonovue | 58 | - | Sn = 84% | Sn = 73% | - |
Sp = 76% | Sp = 61% | ||||||
Kitano et al[15] 2012 | Prospective | Sonazoid | 277 (PC-204, NET-19, CrP-46, Other-8) | 0.3 | Sn = 95% | - | Sn = 92%1 |
Sp = 89% | Sp = 100% | ||||||
Lee et al[16] 2013 | Prospective | Sonovue | 37 (PC-28, NET-5, CP-2) | - | Sn = 93% | - | - |
Sp = 86% | |||||||
PPV = 93% | |||||||
NPV = 75% | |||||||
Acc = 92% | |||||||
Gincul et al[14] 2014 | Prospective | Sonovue | 100 | 0.4 | Sn = 96% | Sn = 95% | |
(PC-69, | Sp = 94% | Sp = 93% | |||||
NET-10, CP-13, | PPV = 94% | PPV = 100% | |||||
Other-8) | NPV = 97% | NPV = 100% | |||||
Acc = 91% | Acc = 86% | ||||||
Park et al[17] 2014 | Retrospective | Sonovue | 90 | - | Sn = 91.9% | - | Sn = 90% |
Sp = 67.8% | Sp = 100% | ||||||
Dietrich et al[21] 2016 | Retrospective | Sonovue | 394 | Sn = 92% | - | - | |
PC-146 | |||||||
NET-156 |
- Citation: Seicean A, Mosteanu O, Seicean R. Maximizing the endosonography: The role of contrast harmonics, elastography and confocal endomicroscopy. World J Gastroenterol 2017; 23(1): 25-41
- URL: https://www.wjgnet.com/1007-9327/full/v23/i1/25.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i1.25